Title

Gastric Cancer: Descriptive Epidemiology, Risk Factors, Screening, and Prevention

Document Type

Journal Article

Publication Title

Cancer Epidemiology, Biomarkers & Prevention

Publication Date

2014

Date Added

2022-09-07

Abstract

Abstract Less than a century ago, gastric cancer was the most common cancer in the United States and perhaps throughout the world. Despite its worldwide decline in incidence over the past century, gastric cancer remains a major killer across the globe. This article reviews the epidemiology, screening, and prevention of gastric cancer. We first discuss the descriptive epidemiology of gastric cancer, including its incidence, survival, mortality, and trends over time. Next, we characterize the risk factors for gastric cancer, both environmental and genetic. Serologic markers and histological precursor lesions of gastric cancer and early detection of gastric cancer using these markers are reviewed. Finally, we discuss prevention strategies and provide suggestions for further research. Cancer Epidemiol Biomarkers Prev; 23(5); 700–13. ©2014 AACR.

DOI

10.1158/1055-9965.EPI-13-1057

Keywords

Health

Disciplines

Biology

Comments/Extra Notes

Additional author: Kamangar, Farin

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